About JAVYGTOR
How JAVYGTOR works
Restriction of dietary phenylalanine intake remains the first line therapy for patients with PKU, requiring a decrease in the intake of natural protein and replacing it with a protein (amino acid mixture) source devoid of Phe.1
In addition to dietary therapy, approximately 20-56% of affected patients respond to sapropterin dihydrochloride therapy.2
Sapropterin dihydrochloride is the active ingredient in JAVYGTOR and is a proven treatment for PKU. JAVYGTOR is an orally active BH4 co-factor, which stimulates residual activity in the phenylalanine hydroxylase (PAH) enzyme, in patients who respond to treatment.2
Your patients are eligible for JAVYGTOR without a trial if they have responded to sapropterin therapy previously. For patients new to sapropterin therapy, the ACMG recommends a trial to assess their responsiveness to the medication.1
A proven treatment for PKU
JAVYGTOR is a treatment for patients with PKU who want to remain on sapropterin dihydrochloride treatment while benefitting from Cycle Vita, which provides individualized support* as unique as your patients.
The same proven sapropterin dihydrochloride Tablets for Oral Use and Powder for Oral Solution2
The expertise of Cycle Vita, a dedicated hub support platform, to support your patients’ treatment journey
Prescribing JAVYGTOR
To prescribe JAVYGTOR to your patients please complete a JAVYGTOR enrollment form.
If you have any questions, please contact the Cycle Vita team at
+1 (888) 360-8482.
References
1. Vockley J., et al; for the American College of Medical Genetics and Genomics Therapeutic Committee. Phenylalanine hydroxylase deficiency: diagnosis and management guideline. Genet Med. 2014;16(2):188-200. doi:10.1038/gim.2013.157.
2. JAVYGTOR (sapropterin dihydrochloride). Prescribing Information. Dr Reddy’s Laboratories Ltd.
*Some areas of support may not be accessible to all patients. Eligibility criteria may apply to ensure compliance with all applicable federal and state requirements, and benefits may be limited to commercially insured patients only. For more detailed information about eligibility, terms and conditions, please contact the Cycle Vita team at +1 (888) 360-8482.